Treatment effects on Hematological Parameters and Serum Biochemical Profile of Lulu Cattle Infected with Bovine Anaplasmosis

Abstract

Anaplasmosis is a vector-borne, infectious blood disease of cattle caused by the rickettsial parasites, Anaplasma marginale and Anaplasma centrale. This parasite infects the red blood cells and causes severe anemia. Ticks are a common vector of this disease. The estimates of biochemical constituents are the prerequisites to diagnose patho-physiological disorders in cattle. This study aimed to compare the hematological and serum biochemical parameters aftereffect of treatment of antibiotics on infected Lulu cattle [Bos taurus]. This study further investigated the effectiveness of antibiotics with different routes of administration: intramuscular and intravenous. Hematological and serum biochemical profiles were taken from 31 Lulu cattle infected with Bovine Anaplasmosis and 14 treated Lulu cattle. Due to blood parasitic infestation, white blood cells increased to 17.8 and dropped significantly to normal value 12.7 after treatment. Lymphocyte levels significantly decreased after treatment from a diseased condition of 13.3 down to 7.92. Other hematological parameters such as Neutrophil, Eosinophil and Basophil were not significantly different before and after treatment. Serum biochemical profiles including glucose, total protein, albumin, calcium and phosphorous were affected by Bovine Anaplasmosis but values were not significantly different before and after treatment. Further, we found that intravenous administration of antibiotics is more effective over intramuscular administration route as blood smear showed clear up parasites after 10 days treatment by administration of drug by I/V mode. Our results indicate that hematological values return to normal levels after effective treatment using antibiotic.